TeamSpeak is flexible, powerful, scalable software which enables people to speak with one another over the Internet. TeamSpeak consists of both client and server software. The server acts as a host to multiple client connections, capable of handling literally thousands of simultaneous users. This results in an Internet based conferencing solution that works in a variety of applications such as team mates speaking with one another while playing their favorite online game, facilitating interoffice communication among coworkers, or simply for personal communication with friends and family.

Website: http://www.teamspeak.com/